Washington, DC - A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in near-atomic detail, the architecture of a metabolic enzyme bound to a drug that blocks its activity. This advance provides a new path for solving molecular structures that may revolutionize drug development, noted the researchers.

Washington, DC - Gene therapy for Leber congenital amaurosis (LCA), an inherited disorder that causes vision loss starting in childhood, improved patients’ eyesight and the sensitivity of the retina within weeks of treatment. Both of these benefits, however, peaked one to three years after treatment and then diminished, according to results from an ongoing clinical trial funded by the National Eye Institute (NEI), part of the National Institutes of Health.

Scottsdale, Arizona - Tinnitus involves hearing noise in one or both ears that is not caused by an external sound. Tinnitus is common, but it is not a condition on its own. Rather, it is a symptom of another underlying condition.

Imperial, California - Phosphatidylserine is a dietary supplement that has received some interest as a potential treatment for Alzheimer's disease and other memory problems. Several studies with phosphatidylserine indicate improved cognitive abilities and behaviors. However, improvements lasted only a few months and were seen in people with the least severe symptoms.

Rochester, Minnesota - Ovarian cancer is a type of cancer that begins in the ovaries. Women have two ovaries, one on each side of the uterus. The ovaries - each about the size of an almond - produce eggs (ova) as well as the hormones estrogen and progesterone.

Phoenix, Arizona - Ultraviolet (UV) rays from the sun can cause skin damage in as little as 15 minutes. Prolonged exposure and damage can lead to various forms of skin cancer, many of which, thankfully, are preventable. The sun isn’t the only skin-damaging predator - tanning beds, smoking and unhealthy diet can also have ill effects on the body’s outer layer.